• Outcome Disparities in Total Knee and Total Hip Arthroplasty among Native American Populations.
  Ryan SP, Seyler TM, Bolognesi MP.Rechenmacher AJ, Case A, Wu M
  No prior racial disparities studies in total knee arthroplasty (TKA) and total hip arthroplasty (THA) have specifically evaluated outcomes among American Indian or Alaska Native (AIAN) patients. We hypothesized that AIAN patients have worse outcomes than White patients after controlling for demographics and comorbidities.
• Comorbidity Burden Contributing to Racial Disparities in Outpatient Versus Inpatient Total Knee Arthroplasty.
  Wu M, Belay E, Cochrane N, O'Donnell J, Seyler T.
  Outpatient total knee arthroplasty (TKA) is increasingly common in the setting of early-recovery protocols, value-based care, and removal from the inpatient-only list by the Centers for Medicare & Medicaid Services. Given the established racial disparities that exist in different aspects of total joint arthroplasty, we aimed to investigate whether racial and ethnic disparities exist in outpatient compared with inpatient TKA.
• Efficacy of common antiseptic solutions against clinically relevant microorganisms in biofilm.
  O'Donnell JA, Wu M, Cochrane NH, Belay E, Myntti MF, James GA, Ryan SP, Seyler TM.
  Periprosthetic joint infections (PJIs) are among the most devastating complications after joint arthroplasty. There is limited evidence on the efficacy of different antiseptic solutions on reducing biofilm burden. The purpose of the present study was to test the efficacy of different antiseptic solutions against clinically relevant microorganisms in biofilm.
• Preoperative Weight Loss and Postoperative Weight Gain Independently Increase Risk for Revision After Primary Total Knee Arthroplasty.
  Kim BI, Cochrane NH, O'Donnell JA, Wu M, Wellman SS, Ryan S, Seyler TM.
  The current American Association of Hip and Knee Surgeons (AAHKS) guidelines recommend preoperative weight loss before total knee arthroplasty (TKA) in patients with body mass index (BMI) ≥40 kg/m2. However, there is a paucity of evidence on TKA outcomes after preoperative weight loss. This study therefore evaluated predictors of preoperative and postoperative BMI changes and their impact on outcomes after TKA.
• Efficacy of Common Antiseptic Solutions Against Clinically Relevant Planktonic Microorganisms.
  O'Donnell JA, Wu M, Cochrane NH, Belay E, Myntti MF, James GA, Ryan SP, Seyler TM.
  Prosthetic joint infections (PJIs) are among the most devastating complications after joint replacement. There is limited evidence regarding the efficacy of different antiseptic solutions in reducing planktonic microorganism burden. The purpose of this study was to test the efficacy of different antiseptic solutions against clinically relevant planktonic microorganisms.
• An ACS-NSQIP Analysis of Unicompartmental Knee Arthroplasty Trends from 2013 to 2018.
  Cochrane N, Belay E, Wu M, O'Donnell J, Kim B, Seyler T.
  Unicompartmental knee arthroplasty (UKA) volume has increased with advances in implant design, perioperative protocols, and patient selection. This study analyzed national trends of UKA from 2013 to 2018 and the relationship between patient demographics and postoperative outcomes. Data on UKA (CPT 27446) from 2013 to 2018 was collected from the National Surgical Quality Improvement Program (NSQIP).
• Patterns and Predictors of Weight Change Before and After Total Hip Arthroplasty in Class 2 and 3 Obese Patients.
  Wu M, Cochrane NH, Kim B, Belay ES, O'Donnell J, Ryan SP, Jiranek WA, Seyler TM.
  This study aimed to better understand body mass index (BMI) change patterns and factors associated with BMI change before and after total hip arthroplasty (THA) in Class 2 and 3 obese patients, and assess if preoperative or postoperative BMI change affects postoperative clinical outcomes.
• Racial and Ethnic Disparities in the Imaging Workup and Treatment of Knee and Hip Osteoarthritis.
  Wu M, Case A, Kim BI, Cochrane NH, Nagy GA, Bolognesi MP, Seyler TM.
  There is limited evidence on sociodemographic differences in osteoarthritis management, particularly in non-African American (AA) minorities. We sought to identify differences in imaging modalities, administration of intra-articular injections, and total joint arthroplasty (TJA) between racial/ethnic groups.
• Effect of commonly used lavage solutions on the polymerization of bone cement.
  Wu M, O'Donnell J, Cochrane N, Ryan S, Belay E, Myntti M, Seyler T.
  Little is known about the impact irrigation solutions have on the material properties of cement used in hip and knee arthroplasty. We sought to compare the effect of three commonly used lavage solutions on cement polymerization.
• Risk Factors for Delayed Discharge and Adverse Outcomes Following Outpatient Billed Total Knee Arthroplasty.
  Belay ES, Cochrane NH, Anastasio AT, Wu M, Bolognesi MP, Seyler TM.
  The volume of outpatient total knee arthroplasty (TKA) has increased with advances in perioperative protocols, patient selection, and recent policy changes regarding insurance authorization. This study analyzed 30-day outcomes from a national database to better understand risk factors for delayed discharge (length of stay [LOS] ≥1), readmission, and reoperation after outpatient TKA.
• Total Hip Arthroplasty in Morbidly Obese: Does a Strict Body Mass Index Cutoff Yield Meaningful Change?
  Cochrane N, Ryan S, Kim B, Wu M, O'Donnell J, Seyler T.
  The number of obese patients seeking total hip arthroplasty (THA) continues to expand despite body mass index (BMI) cutoffs. We sought to determine the outcomes of THA in the morbidly obese patient, and hypothesized they would have comparable outcomes to two cohorts of obese, and normal weight patients.
• Predicting Need for Skilled Nursing or Rehabilitation Facility after Outpatient Total Hip Arthroplasty.
  Belay E, Kelly P, Anastasio A, Cochrane N, Wu M, Seyler T.
  Outpatient classified total hip arthroplasty (THA) is a safe option for a select group of patients. An analysis of a national database was conducted to understand the risk factors for unplanned discharge to a skilled nursing facility (SNF) or acute rehabilitation (rehab) after outpatient classified THA.
• Does Order of Operation Matter in Patients Who Have Concomitant Hip and Spine Pathology?
  Wu M, Kim BI, Schwartz AM, Wellman SS, Cochrane NH, Bolognesi MP, Ryan SP.
  In patients, who have coexisting lumbar spine and degenerative hip disease, there remains uncertainty regarding whether hip or spine surgery should be performed first. We hypothesized that undergoing total hip arthroplasty (THA) would protect against subsequent lumbar spine surgery (LSS) in patients who have 'hip-spine syndrome.'
• Risk Factors for Early Readmission and Reoperation After Outpatient Total Hip Arthroplasty.
  Cochrane NH, Belay ES, Kim B, Wu M, O'Donnell J, Ryan S, Bolognesi MP, Seyler TM
  Outpatient total hip arthroplasty (THA) is a safe option for select patients. The purpose of this study was to analyze a national database and understand risk factors that lead to unplanned early readmission and reoperation after outpatient THA. The National Surgical Quality Improvement Program database was used to collect outpatient THAs performed from 2013 to 2020.
• Assessing the Diagnostic Accuracy of Next-Generation Sequencing in Patients With Antibiotic Spacers Before Reimplantation.
  Kildow BJ, Cochrane N, Kelly PJ, O'Donnell JA, Wu M, Lyden E, Jiranek WA, Seyler TM.
  Use of molecular sequencing modalities in periprosthetic joint infection diagnosis and organism identification has gained popularity recently. To date, there is no diagnostic test that reliably predicts infection eradication in patients with antibiotic spacers. The purpose of this study was to compare the diagnostic accuracy of next-generation sequencing (NGS), culture, the Musculoskeletal Infection Society (MSIS) criteria, and the criteria by Parvizi et al in patients with antibiotic spacers.
• Cutibacterium Positive Cultures in Total Hip Arthroplasty: Contaminant or Pathogen?
  Cochrane NH, Kim BI, Wu M, O'Donnell JA, Seidelman JL, Jiranek WA.
  Cutibacterium spp. is an emerging pathogen in total hip arthroplasty (THA) that is not well evaluated in the literature. This study reported on the presentation and management of THA complicated by positive intraoperative Cutibacterium cultures.
• Surgical Treatment of Solitary Periarticular Osteochondromas About the Knee in Pediatric and Adolescent Patients: Complications and Functional Outcomes.
  Wu M, Zheng ET, Anderson ME, Miller PE, Spencer SA, Heyworth BE.
  Solitary osteochondromas, or osteocartilaginous exostoses (OCEs), represent the most common benign bone tumor. Despite frequently causing symptoms about the knee in younger populations, there is minimal previous literature investigating surgical treatment.
• Does a fibula-sparing approach improve outcomes in tibiotalocalcaneal arthrodesis?
  Wu M, Scott D, Abar B, Schiff A, Pellegrini M, Nunley JA, Adams SB.
  Tibiotalocalcaneal (TTC) arthrodesis is considered a salvage procedure for either complex deformity or arthritis about the hindfoot, and can be performed via fibula-resection (FR) or fibula-sparing (FS) approaches. The primary aim of this study was to investigate differences in outcomes in FR versus FS TTC arthrodeses.
• Outcomes After Revision Anterior Shoulder Stabilization: A Systematic Review.
  Lau BC, Johnston TR, Gregory BP, Bejarano Pineda L, Wu M, Fletcher AN, Hu JH, Ledbetter L, Riboh JC.
  Primary shoulder stabilization is successful, but there continues to be a risk of recurrence after operative repair, particularly in the young athlete. It is important for surgeons to understand the outcomes after various revision stabilization techniques to best counsel patients and manage expectations.
• Return to Play After Revision Anterior Shoulder Stabilization: A Systematic Review.
  Lau BC, Pineda LB, Johnston TR, Gregory BP, Wu M, Fletcher AN, Ledbetter L, Riboh JC.
  Revision shoulder stabilizations are becoming increasingly common. Returning to play after revision shoulder stabilizations is important to patients.

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